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الجمعة، 13 يناير، 2012

biochemical changes of hyperemesis graviderum:


biochemical changes of hyperemesis graviderum:

د/كمال شرحها كده ف المحاضره و جت ف امتحان 2002 ... نقلا عن احمد الصاوى
-vomiting ...> tachycardia & fluid loss
-fluid loss ...> hypotension & hypovolaemia
-early ketosis :
vomiting with each meal .....> body depends on internal source of energy ( glycogen then fat ) without kreb's cycle ....> incomplete oxidation of acetate ....> ketosis
N.B ... alkalies manage ketosis
-with long standing starvation ....> acidosis ....> affect vomiting center ...> more vomiting .....> acidosis ...> vicious circle
-pathological changes in organs:
heart ... brown atrophy
kidney ... tubular damage
liver ... fatty infiltration
brain ... degeneration in basal ganglia
retina .... hemorrhage & detachement
periph. nerves ... polyneuritis

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